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目的:本实验采用大鼠缺血再灌注模型,探讨缬沙坦对大鼠心肌缺血再灌注损伤的作用及机制。方法:26只SD大鼠随机分为3组:sham组(大鼠冠状动脉左前降支只穿线,不结扎)、I/R组(大鼠冠状动脉左前降支结扎)和valsartan组(以缬沙坦药
OBJECTIVE: To investigate the effect of valsartan on myocardial ischemia-reperfusion injury in rats and its mechanism by using rat model of ischemia-reperfusion. Methods: Twenty-six Sprague-Dawley rats were randomly divided into three groups: sham group (only left anterior descending coronary artery was ligated and not ligated), I / R group (left anterior descending coronary artery ligation) and valsartan group Sartan medicine