L-4F suppresses pancreatic cancer progression associate with inhibiting inflammation in mouse pancre

来源 :中国免疫学会第十届全国免疫学学术大会 | 被引量 : 0次 | 上传用户：jueqidf_1

【摘要】

：

Objective: Pancreatic cancer is an aggressive malignancy and unresponsive to conventional radiation and chemotherapies.Therefore, the development of novel immune therapeutic strategies is urgently nee

【作者】

：

Meiyu Peng Qi Zhang Shuyu Fu Zhi Yao Rongxin Zhang

【机构】

：

Weifang Medical University;Tianjin Medical University

【出处】

：

中国免疫学会第十届全国免疫学学术大会

【发表日期】

：

2015年10期

【关键词】

：

Pancreatic cancer L-4F Inflammation STAT3 MAPK

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

其他文献

恶性肿瘤血清细胞因子芯片表达谱临床应用的初步研究

研究背景：随着肿瘤免疫学的发展，细胞因子的检测方法不断更新。液相芯片技术是20世纪90年代兴起的集合流式细胞技术、激光技术、数字信号处理技术及传统化学技术为一体的新型检测技术。较之传统的固相芯片，液相芯片技术检测结果更准确、信息质量更稳定、可重复性更好。

会议

液相芯片肿瘤细胞因子

Development of sandwich ELISA for detecting bovine β-lactoglobulin allergenic residues by specific p

Background: Cows milk is one of the most common allergenic foods, especially in infant and children, and β-lactoglobulin (BLG) is the main allergen in cows milk.

会议

Bovine β-1actoglobulinMilk allergensAllergic residuesELISA

Tumor therapeutics work as stress inducers to enhance tumor sensitivity to NK cell cytolysis by upre

Background: Immune cells are believed to participate in initiating anti-tumor effects during regular tumor therapy such as chemotherapy, radiation, hyperthermia and cytokine injection.

会议

tumor therapyNK cellsB7H6NKp30

新型MIP-2γ/GM-CSF融合蛋白对DC的双重生物学功能及相关机制研究

目的：制备新型MIP-2γ/GM-CSF细胞因子融合蛋白，研究其趋化和激活DC的双重生物学功能.方法：通过基因工程方法构建高表达MIP-2γ/GM-CSF融合蛋白的2种P.pastoris酵母工程菌株，并优化发酵、纯化条件，制备了高纯度的MIP-2g/hGM-CSF、MIP-2g/mGM-CSF融合蛋白.首先以Transwell体系检测融合蛋白对树突状细胞DC的诱导迁移效应.接着以流式细胞仪分析重

会议

巨噬细胞炎性蛋白-2γ融合蛋白趋化激活DC

Functions of miR-146a and miR-222 in Tumor-associated Macrophages of Breast Cancer

Object: Tumor associated macrophages (TAMs) play critical roles in promoting tumor progression and invasion.However, the molecular mechanism for the regulation of TAM remains to be further investigate

会议

TAMmiR-146amiR-222PolarizationRecruitment

Specific anti-HBsAg CAR modified T cells suppress HBV-associated hepatocellular carcinoma progressio

Background and Purposes: A specific and strong T-cell response against HBV does not occur in patients with HCC.Adoptive T cell therapy can transfer therapeutic immunity.

会议

Tumor therapyHCCCAR-T

The negative costimulatory molecule B7-H3 promotes tumor stemness and metastasis via induction of ep

Introduction: Colorectal cancer is a serious threat to human health.And metastasis is the key factor of poor prognosis.Recently, we have found that the negative costimulatory molecule B7-H3 is highly

会议

Colorectal cancerB7-H3StemnessEpithelial-to-mesenchymal transitionMetastasis

γδT17细胞在人大肠免疫调控中的作用及机制研究

目的：肿瘤发展与慢性炎症尤其是IL-23/IL-17通路相关。然而，人大肠癌组织IL-17的来源及其分泌细胞促进肿瘤进展的机制尚不清楚。方法：我们通过多色流式分析及原代细胞分离技术研究人大肠癌及配对组织IL-17的细胞来源及炎性细胞组成。

会议

γδT17细胞大肠癌免疫抑制MDSCs

Paracrine mechanism of interleukin-17B receptor potentiates tumor growth and migration via AKT/β-cat

Inflammation is a critical component involved in tumor progression.IL-17 cytokine family, though still young since discovery, has recently emerged as important players in diseases.

会议

IL-17B/IL-17BR axisAKT/β-catenin pathwaySternnessMGC-803Gastric cancer

Effects of upregulation of Id3 in human lung adenocarcinoma cells on proliferation, apoptosis, mobil

Objectives:The inhibitor of DNA binding/differentiation 3 (Id3) protein is a helix-loop-helix transcription factor and might have an important role in cell proliferation and differentiation.

会议

Id3A549ProliferationApoptosisTumorigenicity

L-4F suppresses pancreatic cancer progression associate with inhibiting inflammation in mouse pancre

其他学术论文