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Background To assess the left ventricular function of ASD with PAH patients and to determine whether the left ventricular function and pulmonary pressure could nm better after transcatheter closure by echocardiography.Methods There were 75 patients with ASD aged ≥40 years, 15 males and 60 females, divided them two groups.(1)PAH group: 36 patients with ASD associated with PAH, 6 males and 30 females, aged from 41 to 74 years (mean(51.7±9.3) years), ASD diameter aged from 15 to 37 (mean 22.9±8.1) mm by transthoracic echocardiogram (TTE).