D-3-phosphoglycerate dehydrogenase (PGDH) from Escherichia coli catalyzes the first critical step in serine biosynthesis[1], and can be allosterically inhib
The aspartate receptor (Tar) in E.coli, a crucial component in the bacterial sensory systems that mediate chemotaxis, has been intensively studied for years
Intrinsically disordered proteins (IDPs) show little ordered structures under physiological conditions.Roughly 10% of proteins in various genomes have been
Computationally designing novel proteins that can bind to a specific target protein is promising yer challenging, as binding and folding need to be consider
SLX4 interacts with several endonucleases to resolve structural barriers in DNA metabolism.SLX4 also interacts with telomeric protein TRF2 in human cells.Th
A unifying theme in biology is that function is reflected in structure, such as the highly specialized structure of a birds wing and the folded conformation
Molecular chaperones play an essential role in assisting the folding of a myriad of nascent peptides to form different biologically active proteins.Therefor
The ability to selectively modify proteins with fluorescent probes has greatly facilitated both in vitro and in vivo studies of protein structure and functi
Conotoxins are peptide neurotoxins produced by cone snails to prey and for defense.These conotoxins target on different ion channels, receptors, or neurotra