• 不 限
  • 期刊论文
  • 硕博论文
  • 会议论文
  • 报 纸
  • 英文论文
  2. 您的位置
  3. 首页
  4. 会议论文
  5. Comparison of toxic reaction of Zhuanggu-guanjie pill in different model rats of osteoarthritis

Comparison of toxic reaction of Zhuanggu-guanjie pill in different model rats of osteoarthritis

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户：kyleSun81
【摘 要】
：
Aim: Zhuanggu-guanjie pill (ZGGJP) is a kind of effective chinese patent drug to osteoarthritis(OA) with kidney deficiency (KDOA), but certain side effects occur in clinic.This study was to determine
【作 者】
：
Dan LUO Cheng LU Sheng-long JING Hong-yan ZHAO Xiao-juan HE Peng XU Min-zhi WANG Xue-gong Xu Ai-ping LU Cheng XIAO 
【机 构】
：
China-Japan Friendship Hospital,Beijing 100030,China;Beijing University of Traditional Chinese Medic
【出 处】
：
The 12th Meeting of the Asia Pacific Federation of Pharmacol
【发表日期】
：
2013年4期
【关键词】
：
Zhuanggu-guanjie pill osteoarthritis kidney deficiency liver toxicity 
下载到本地 , 更方便阅读
下载此文 赞助VIP
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Aim: Zhuanggu-guanjie pill (ZGGJP) is a kind of effective chinese patent drug to osteoarthritis(OA) with kidney deficiency (KDOA), but certain side effects occur in clinic.This study was to determine whether ZGGJP induced different toxicity in rats with KDOA compared to those in normal rats.
其他文献
Bis-(2-ethylhexyl) phthalate suppresses myogenic differentiation and promotes adipogenic differentia
Aim: Bis-(2-ethylhexyl) phthalate (DEHP) is a manufactured chemical that makes plastic more flexible.Exposure to DEHP has recently been shown to possess a potential health hazard in premature infants
会议
bis-(2-ethylhexyt) phthalatemyogenesisadipogenesisskeletal muscle progenitor
The effects of high-purine diet on the blood pressure and kidney function of mice
Aim: Referring to the relation between hypertension and long-term high-purine diet, we established the hypertension model mice by feeding with high-purine food, which is similar to human diseases.Meth
会议
hypertensionmodelmicerenal functionhigh purine
Discovery of a potent and orally-available D-amino acid oxidase inhibitor for the management of chro
Aim: It has been shown that spinal D-amino acid oxidase (DAAO) might be a potential molecular target for the treatment of chronic pain and morphine tolerance to analgesia.This study evaluated the in v
会议
DAAO inhibitorCompound 15morphine toleranceneuropathic painformalin-induced
GLP-1 receptor promotes osteogenic differentiation of bone marrow mesenchymal stem cells by Improvin
Aim: The coordinated balance between osteoblastic bone formation and osteoclastic bone resorption is a kind of key target of anti-osteoporotic agents.Now among therapeutics currently used to treat ost
会议
GLP-1 receptorsExendin-4bone mesenchymal stem cells (BMSCs)osteoporosisWnt/β
Severe adverse reactions of vitamin K1 injection are anaphylactoid reaction, not anaphylaxis
Aim: Adverse reactions of vitamin K1 (VK1) injection are considered as anaphylaxis.The study is to clarify a hypothesis that it is an anaphylactoid reaction.Methods: Beagle dogs were administered intr
会议
vitamin K1anaphylactoid reactionsanaphylaxis
IOP lowering effect of losartan and latanoprost in oculohypertensive rats: A comparative evaluation
Aim: To evaluate the intraocular pressure (IOP) lowering effect of losartan potassium in rats with steroid-induced ocular hypertension and compare the IOP lowering effects with that of latanoprost.Met
会议
IOPsteroid-inducedratslosartanlatanoprost
Establishment of mitochondrial toxicity model in HepG2 cell
Aim: In recent years, marketed drugs withdrawn and termination of new drug study in pre-clinical/clinical stage due to mitochondrial-related side effects were uncommon.In this project, we established
会议
mitochondrial toxicityATPglucose mediumgalactose medium
Respiratory syncytial virus induces glucocorticoid-insensitivity in airway epithelial cells
Aim: Respiratory syncytial virus (RSV) is a major cause of acute respiratory, which responds inadequately to anti-inflammatory actions of glucocorticoids (GC).RSV triggers expression and activity of c
会议
GCsvirusasthma exacerbation
Important role of PKA pathway in endothelial cell migration induced by VEGF and modulation by noriso
Aim: To investigate the role of PKA pathway in VEGF-induced endothelial cell migration and modulation by norisoboldine (NOR).Methods: Fibrin bead assay,RT-PCR, Western blot, coimmunoprecipitation, imm
会议
PKA pathwayVEGFendothelial cell migrationnorisoboldine
Hepatoprotective effect of the flavonoid fraction isolated from the flower of Inula britannica again
Aim: The aim of this study was to investigate the mechanism and the protective effect of Inula britannica flower flavonoids (IBFF) on antioxidants and the inhibition of inflammation in liver injury.Me
会议
IBFFacute liver injuryD-Galantioxidationanti-inflammation