Reversing Metabolic Dysfunctional in Children: What is the Best Biomarker or Biosensor?

来源 :2013第三届内分泌与代谢大会暨2013第二届糖尿病大会 | 被引量 : 0次 | 上传用户:az4620
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Our knowledge of adipose tissue has changed from an inert energy storage tissue to an active endocrine organ, which communicates with central and peripheral organs through the synthesis and secretion of a number of molecules.These adipokines molecules potentially fulfill the role of biomarkers and biosensors.For example the production and secretion of adipokines may play a role in sensing nutrients and therefore measurement of these can increase our understanding of the metabolic homeostasis of the system.We also know that different nutrients provoke different hormonal responses, and those hormonal responses determine how much fat is accumulated, although limited evidence of this exists in children.
其他文献
Obesity has become a pandemic problem over the past few years, raising major health concerns across many nations.Abdominal obesity in particular, is frequently associated with hypertension, insulin re
会议
As a heterogeneous syndrome, PCOS is by definition a constellation of reproductive and metabolic abnormalities with no specific diagnostic test.Until now, three criteria have been proposed based on th
会议
HDL is an endogenous heterogeneous lipoprotein, acting both as cholesterol donors for adrenal steroidogenesis and as cholesterol acceptors for foam cells in atherosclerotic lesions.ABCA 1 and SR-BI ar
会议
Type 2 Diabetes & obesity have become modern day epidemics with 371 million people living with it, & expected to be over 500 million in 2025.More than 4.8 million people die annually.Osteoporosis is t
会议
Although osteoporosis is often considered a disease primarily affecting females, within the past two decades it has become apparent that osteoporosis is not solely a female disease.It affects an estim
会议
Hypogonadism was defined as morning serum testosterone level less than 300 ng/dL and absence of fertilization.The diagnosis is based on clinical signs and symptoms plus laboratory confirmation via the
会议
Prader-Willi syndrome (PWS) is the most common form of genetic obesity and it occurs in approximately 1 in 25,000 live births.PWS is characterized by neonatal hypotonia, feeding problems and failure t
会议
Recent studies demonstrate that the effects of autophagy on isnulin resistance are dependent on cell types.Defective hepatic autophagy in obesity has been reported to promote ER stress and cause insul
会议
Trying to solve the main bottle neck of Brazilian beef industry our research team is dedicate to study Nellore puberty.Although very resistant to environmental pressure Nellore cattle is one year behi
会议
In the course of care and evaluation of thyroid function, several nursing home residents were unexpectedly found to have secondary hypothyroidism.Further laboratory evaluation of their pituitary funct
会议