【摘 要】
：
Protein phosphorylation is one of the most important post-translational modifications.Organisms utilize this reversible reaction of proteins to control many cellular activities, including signal trans
【机 构】
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Department of Functional Molecular Science Graduate School of Biomedical Sciences Hiroshima Universi
【出 处】
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BIT Life Sciences 1st Annual World Cancer Congess-2008(2008中
论文部分内容阅读
Protein phosphorylation is one of the most important post-translational modifications.Organisms utilize this reversible reaction of proteins to control many cellular activities, including signal transduction, apoptosis, gene expression, cell cycle progression, cytoskeletal regulation, and energy metabolism.Abnormal protein phospborylation is deeply related to carcinogenesis.Methods for monitoring the phosphorylation status of proteins are, thus, very important with respect to the evaluation of the basis for understanding the molecular origins of cancers and for the drug design.
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