The protective effect of RGDs on acute lung injury in cecal ligation and puncture-induced sepsis mic

来源 :中华医学会第22次全国麻醉学术年会 | 被引量 : 0次 | 上传用户:mountaineer
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
One of the common lethal complications of sepsis, a major cause of morbidity and mortality in patients with severe trauma and so on, is acute lung injury.The purpose of this study was to elucidate the possible beneficial effects of synthetic Arg-Gly-Asp-Ser (RGDs) peptide on acute lung injury in a mice model of sepsis through wisp1-lntegrinβ6 pathway.
其他文献
Endothelial barrier dysfunction is the hallmark of acute lung injury or acute respiratory distress syndrome, involving complicated inflammatory activation and cellular changes, which is far away from
Injury to the central nervous system has baffled the human being for ages.Until now, no medical measurements have been proved clinically to reduce CNS injury effectively except for tPA against ischemi
会议
Previous clinical studies have well demonstrated a strong relationship between sustained chronic hyperglycemia (measured by HbA1c) and diabetic complications.Now, a growing body of evidence shows that
Metabolomics follows the changes in concentrations of endogenous metabolites,which may reflect various disease states as well as systemic responses to environmental, therapeutic, or genetic interventi
The cardioprotective effects of remifentanil preconditioning (RPC) against ischemia reperfusion injury have been demonstrated in intact and isolated rat hearts.1,2 This study aimed to investigate the
Background In-hospital strokes account for 6.5%~15% of total strokes.Half of them are peri-operative strokes.Thrombolysis and new antiplatelet drugs have significantly improved prognosis of ischemic s
Endotoxic shock is a disease process caused by a severe underlying infection.In the case of Gram-negative bacterial infections, the release of endotoxin or lipopolysaccharide (LPS) from the bacterial
会议
Objective 1.Obsevring the dissolve effect of collagenase on the hernial disc with different CT number.2.Obsevring the the relationship between effect of collagenase for treatment the herniation of cer
会议
Objective To investigate the effect of intrathecal injection with PKC inhibitor Staurosporine on pain behaviour and spinal microglia activation in rats with shin bone cancer pain.Methods One hundred a
To compare the effects of central venous catheterization by surgical operation or by ultrasound-guided puncture, explore the feasibility of Ultrasound-guided central venous catheterization in the porc