Diabetic nephropathy (DN) is the leading cause of end-stage renal disease accounting for more than 50 %of the patients.DN is characterized by histological change
Animals behave differently in response to visual cues with distinct ecological meaning,a crucial strategy for their well-being and survival.Although this is
Somatostatin secretion from islet delta-cells plays an important role in regulating islet function and is tightly controlled by environmental changes.Activa
Sympathetic nerve in heart is essential in heart physiology and diseases,because sympathetic nerve release catecholamines to regulate cardiac cells includin
Sympathetic nerve in heart is essential in heart physiology and diseases,because sympathetic nerve release catecholamines to regulate cardiac cells includin
We have shown that hypoxia reduces plasma insulin,which correlates with corticotropin-releasing hormone(CRH)receptor 1(CRHR1)in rats,but the mechanism remai
In mammals, active DNA demethylation involves oxidation of 5-methylcytosine (5mC) into 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC) by Tet dioxygenases
Primed enhancers are marked by histone H3K4 mono-methylation (H3K4me1), and the conversion to active enhancers involves acetylation of histone H3K27 (H3K27Ac).