Bone marrow-derived mesenchymal stem cells suppress lymphocyte proliferation and prevent graft-versu

来源 :2014中国器官移植大会 | 被引量 : 0次 | 上传用户：a2619040

【摘要】

：

Objeetive:Bone marrow-derived mesenchymal stem cells (MSCs) could exert a potent immunosuppressive effect,and therefore may have a therapeutic potential in T-cell-dependent pathologies.In the present

【作者】

：

Ping ZHU Jia-xinLI Jia-ni LI Hui-ming GUO Cong LU Ji-mei CHEN Shao-yi ZHENG Jian ZHUANG

【机构】

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Guangdong General Hospital

【出处】

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2014中国器官移植大会

【发表日期】

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2014年5期

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Objeetive:Bone marrow-derived mesenchymal stem cells (MSCs) could exert a potent immunosuppressive effect,and therefore may have a therapeutic potential in T-cell-dependent pathologies.In the present study,we aimed to determine whether MSCs could be used to control graft-versus-host disease (GvHD),a major cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (HSCT).

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Bone marrow-derived mesenchymal stem cells suppress lymphocyte proliferation and prevent graft-versu

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