Human Oral Squamous Cell Carcinoma Favors the Prevalence of CD4+FOXP3+ IL-17-producing Tumor Infiltr

来源 :2011第四届世界癌症大会 | 被引量 : 0次 | 上传用户：sdfsfd454554

【摘要】

：

【作者】

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Jean-San Chia

【机构】

：

Graduate Institute of Immunology College of Medicine National Taiwan University Taiwan

【出处】

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2011第四届世界癌症大会

【发表日期】

：

2011年3期

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　　Oral squamous cell carcinoma (OSCC) and other head and neck squamous carcinoma constitute a microenvironment characterized by the infiltration of distinct inflammatory cells, predominantly T cells, into the stroma between tumor nests and the surrounding regions.These tumor infiltrating lymphocytes (TILs) may be involved in the modulation of antitumor immunity or tumor promoting inflammation.The pro-inflammatory Th 17 and anti-inflammatory regulatory T (Treg) cells share plasticity in the expression of IL-17 and FOXP3, but their mutual presence in human diseases is unclear.

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Human Oral Squamous Cell Carcinoma Favors the Prevalence of CD4+FOXP3+ IL-17-producing Tumor Infiltr

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