【摘 要】
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INTRODUCTION:Coxsackievirus A16 (CVA16) is a main pathogen for hand,foot,and mouth disease (HFMD) worldwide.This study intended to clarify the genetic characteristics of CVA16 associated with HFM in a
【机 构】
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Department of Microbiology,Nanjing Center for Disease Control and Prevention,Nanjing,China
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INTRODUCTION:Coxsackievirus A16 (CVA16) is a main pathogen for hand,foot,and mouth disease (HFMD) worldwide.This study intended to clarify the genetic characteristics of CVA16 associated with HFM in a defined area in Nanjing,China.METHODOLOGY:A total of 175 CVA16 strains isolated from throat swabs during 2011 to 2013 were recruited through sentinel hospitals in Nanjing.We used multiplex polymerase chain reaction (PCR) to amplify the VP1 sequence of local CVA 16 strains and compared their genetic relationship with 138 CVA 16 strains isolated in China and other countries of the world.
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