Regulation of NEDD8 Degradation by NUB1L through the P97VCP Complex

来源 :2013年第四届全国“跨学科蛋白质研究”学术讨论会 | 被引量 : 0次 | 上传用户：chensiren

【摘要】

：

　　NEDD8 is a ubiquitin-like protein which regulates pivotal biological processes by conjugating to client proteins.NEDD8 and neddylation are negatively regula

【作者】

：

刘帅杨慧赵健张宇航宋爱新胡红雨

【机构】

：

中国科学院上海生命科学研究院生物化学与细胞生物学研究所,分子生物学国家重点实验室,上海200031

【出处】

：

2013年第四届全国“跨学科蛋白质研究”学术讨论会

【发表日期】

：

2013年10期

【关键词】

：

NEDD8 Neddylation NUB1L P97/VCP Cullin 1

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　　NEDD8 is a ubiquitin-like protein which regulates pivotal biological processes by conjugating to client proteins.NEDD8 and neddylation are negatively regulated through the proteasomal degradation pathway by NUB1L and its splicing variant NUB1.

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Regulation of NEDD8 Degradation by NUB1L through the P97VCP Complex

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