Peptides from sesame cake reduce oxidative stress and amyloid-β toxicity of Caenorhabditis elegans

• 作 者: Xiaoli Ma Xiaodong Cui Jiao Li Fang Li Zhuanhua Wang
• 机 构: SchoolofLifeScience,ShanxiUniversity,Taiyuan030006,PRChina;KeyLaboratoryofChemicalBiologyandMolecula
• 出 处: 中国生物化学与分子生物学会第十二届会员代表大会暨2018年全国学术会议
• 发表日期: 2018年10期
• 关键词: Peptides from sesame cake Caenorhabditis elegans Alzheimer's disease amyloi

　　Alzheimers disease(AD)is widely recognized as a serious public health problem,of which Amyloid-β(Aβ)-induced oxidative stress and toxicity are suggested as the leading risk factors.Peptides from sesame cake(PSC)are a group of novel bioactive peptides derived from an agricultural by-product.We employed an AD model Caenorhabditis elegans(C.elegans)(CL4176)to study the effects of PSC on Aβ-induced toxicity,oxidative stress and possible molecular mechanism.