扶正消症方的增效减毒作用及处方筛选的实验研究

来源 :世界中医药学会联合会中药药理专业委员会第七届学术会议、全国中药药理联合会第二届学术年会暨第20届中日健康学术研讨会 | 被引量 : 0次 | 上传用户：chen17981

【摘要】

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目的:研究扶正消症方及其减方联合化疗药物环磷酰胺(CTX)对S180荷瘤小鼠抗肿瘤的增效减毒作用,并且为处方筛选提供实验依据.方法:复制小鼠移植性肿瘤S180模型,观察扶正消症方及其减方与CTX合用对进行血细胞数量、肿瘤重量、脾脏、胸腺及肝脏指数的影响,检测肝匀浆中丙二醛(MDA)和超氧化物歧化酶(SOD)的活性,HE染色观察肿瘤组织的病理变化.结果:与CTX组比较,各联合给药组均能够明显的破坏肿

【作者】

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肖思源武璞吕腾王斌

【机构】

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陕西中医学院,陕西咸阳 712046

【出处】

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世界中医药学会联合会中药药理专业委员会第七届学术会议、全国中药药理联合会第二届学术年会暨第20届中日健康学术研讨会

【发表日期】

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2014年5期

【关键词】

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移植性肿瘤扶正消症方环磷酰胺增效减毒作用

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扶正消症方的增效减毒作用及处方筛选的实验研究

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