Neuroinflammation and microglial activation in a rat model of Ataxia Telangiectasia

来源 :The 16th Ataxia-Telangiectasia Workshop (ATW-2015)6th Intern | 被引量 : 0次 | 上传用户：LOVER1122

【摘要】

：

Ataxia-telangiectasia (A-T) is an autosomal recessive disease caused by mutations in the ATM gene.A-T patients are characterised by increased cancer development,radiosensitivity, immunodeficiency and

【作者】

：

Hazel Quek Tara Roberts Sergei Kozlov Magtouf Gatei Mark Bellingham Peter Noakes Nigel Barnett Tomoji Mashimo Martin Lavin

【机构】

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UQCCR Ingham Institute

【出处】

：

The 16th Ataxia-Telangiectasia Workshop (ATW-2015)6th Intern

【发表日期】

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2015年3期

【关键词】

：

rat model neurodegeneration microglia motor neurons cytosolic DNA

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　　Ataxia-telangiectasia (A-T) is an autosomal recessive disease caused by mutations in the ATM gene.A-T patients are characterised by increased cancer development,radiosensitivity, immunodeficiency and progressive neurodegeneration.

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Neuroinflammation and microglial activation in a rat model of Ataxia Telangiectasia

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