【摘 要】
：
The maintenance of genome integrity is important in all cells.To conserve genome integrity, cells developed multiple molecular pathways to repair damaged DNA.Proliferating Cell Nuclear Antigen (PCNA),
【机 构】
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Center for Genomic Integrity,Institute for Basic Science,Ulsan National Institute of Science and Tec
【出 处】
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The 16th Ataxia-Telangiectasia Workshop (ATW-2015)6th Intern
论文部分内容阅读
The maintenance of genome integrity is important in all cells.To conserve genome integrity, cells developed multiple molecular pathways to repair damaged DNA.Proliferating Cell Nuclear Antigen (PCNA), which is a homotrimeric ring-structure complex plays an important role in coordinating the replication fork-associated process during the DNA damage response and replication.PCNA functions as a clamp for DNA replication proteins and a platform for multiple DNA repair enzymes.
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