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  5. CRISPR/Cas9 Facilitates Investigation of Neural Circuit Disease using Human iPSCs:Mechanism of Epile

CRISPR/Cas9 Facilitates Investigation of Neural Circuit Disease using Human iPSCs:Mechanism of Epile

来源 :第八届广州国际干细胞与再生医学论坛暨第四届中国再生细胞生物学年会 | 被引量 : 0次 | 上传用户：jiangfan520
【摘 要】
：
Mutations in SCN1A,the gene encoding α subunit of Nav1.1 channel,can cause epilepsies with wide ranges of clinical phenotypes,which are associated with the contrasting effects of channel loss-of-funct
【作 者】
：
Jingxin Liu Chao Gao Zhiyuan Li 
【机 构】
：
Guangzhou Institutes of Biomedicine and Health,Chinese Academy of Sciences,Guangzhou,China
【出 处】
：
第八届广州国际干细胞与再生医学论坛暨第四届中国再生细胞生物学年会
【发表日期】
：
2015年3期
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　　Mutations in SCN1A,the gene encoding α subunit of Nav1.1 channel,can cause epilepsies with wide ranges of clinical phenotypes,which are associated with the contrasting effects of channel loss-of-function or gain-of-function.
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