A Facile Synthesis of Coumarin-quinolone Hybrids as Potential Novel Antimicrobial Agents

来源 :中国化学会全国第十二届有机合成化学学术研讨会 | 被引量 : 0次 | 上传用户：liyaping121416

【摘要】

：

　　Quinolones containing 3-carboxylic benzopyridone skeletons are an important kind of synthetic antibacterial agents as they are generally well tolerated with

【作者】

：

PengXin-Mei;KannekantiVijayaKumar;SrinivasaRaoAvula;ZhouCheng-He;

【机构】

：

School of Chemistry and Chemical Engineering,Southwest University,Chongqing 400715

【出处】

：

中国化学会全国第十二届有机合成化学学术研讨会

【发表日期】

：

2015年期

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　　Quinolones containing 3-carboxylic benzopyridone skeletons are an important kind of synthetic antibacterial agents as they are generally well tolerated with good treatment effectiveness,broad antibacterial spectrum and favorable pharmacokinetic characteristics.Since the first quinolone drug was discovered in 1960s,the related structural modifications based on 3-carboxylic benzopyridone skeletons have become an extremely attractive topic in antibacterial field,and much effort has been focusing on this topic.

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A Facile Synthesis of Coumarin-quinolone Hybrids as Potential Novel Antimicrobial Agents

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