Induction of ROS generation and NF-kappa B activation in MARC145 cells by a novel Porcine Reproducti

来源 :2013国际猪繁殖与呼吸综合征学术研讨会 | 被引量 : 0次 | 上传用户：xiaohan521325

【摘要】

：

【作者】

：

Y.Yan A.Xin Q.Liu H.Huang Z.Shao Y.Zang L.Chen Y.Sun H.Gao

【机构】

：

Faculty of Animal Science and Technology, Yunnan Agricultural University, Kunming, Yunnan, People's

【出处】

：

2013国际猪繁殖与呼吸综合征学术研讨会

【发表日期】

：

2013年12期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

Introduction:Viral infection is often accompanied by alteration of the intracellular redox state.Reactive oxygen species (ROS) have been shown to function as cellular signaling molecules,influencing a variety of molecular and biochemical processes,such as NF-kappa B.The aim of the present study was to investigate the interaction between reactive oxygen species (ROS) and NF-kappa B during PRRSV infection.Methods:In this study MARC-145 cells were infected with a novel PRRSV isolate from the Yunnan Provence in southwest China (YN-2011,GenBank accession no.JX 857698).

其他文献

Genome-wide analysis of marker genes related to antiviral regulation in PRRSV-infected porcine macro

Specific objectives:Previously,we showed that porcine monocytic cells could be skewed to various activation statuses similar to those described in mice and humans,including M 1 and M2.We hypothesize t

会议

PRRSV type 1 can induce aggravation of infection with a mild virulent Actinobacillus serotype 2 stra

PRRSV is endemic in most pig producing countries of the world and causes disease characterized by abortions and stillbirth,increased pre-weaning mortality and respiratory disorders in growing pigs.The

会议

Identification of differentially expressed proteins in porcine alveolar macrophages infected with vi

Introduction The highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) is still a serious threat to the swine industry.However,the pathogenic mechanism of virulent/attenuate

会议

In vivo impact of deoxynivalenol naturally contaminated feed on porcine reproductive and respiratory

Animal feeds are frequently contaminated with various mycotoxins produced by the secondary metabolism of diverse fungal contaminants.Among these contaminants,deoxynivalenol (DON),also known as vomitox

会议

The susceptibility of porcine myeloid cells to Porcine Reproductive and Respiratory Syndrome Virus 1

Scavenger receptor CD163 and sialic-acid binding lectin CD169 were identified as key receptor molecules for Porcine Reproductive and Respiratory Syndrome Virus (PRRSV),an important arterivirus which r

会议

Swine immunoglobulin lambda-like polypeptide 5, an adaptor of RIG-1 and MDA5, regulates type I Inter

Porcine reproductive and respiratory syndrome virus (PRRSV) infection appears to elicit a week innate immune response.Several nonstructural proteins (NSPs) encoded by PRRSV genome antagonize type I in

会议

Reduction of PRRSV infection in Marc-145 cells that express the exogenous C-terminal domain of non-m

Objective:We have identified,by a monoclonal anti-idiotypic antibody (Mab2-5G2) which functionally mimics PRRSV GP5 protein,non-muscle myosin heavy chain Ⅱ-A (NMHC Ⅱ-A) as a novel cellular receptor on

会议

Experimental infection and comparative genomic analysis of a highly pathogenic PRRSV-HBR strain at d

Background:In China,PRRS is first recognized in 1996 and has become one of the most severe diseases affect swine production.Moreover,an outbreak of highly pathogenic PRRS (HPPRRS),a highly virulent fo

会议

Synergistic effects of sequential infection with highly pathogenic porcine reproductive and respirat

Background:Porcine reproductive and respiratory syndrome virus (PRRSV) is the causative agent of porcine reproductive and respiratory syndrome (PRRS) and porcine circovirus type 2 (PCV2) is associated

会议

USP18 restricts PRRSV growth through alteration of nuclear translocation of NF-kB p65 and p50 in MAR

Although the functions of porcine respiratory and reproductive syndrome virus (PRRSV) proteins are increasingly understood,the roles of host factors in modifying infection are less well understood.Gro

会议

Induction of ROS generation and NF-kappa B activation in MARC145 cells by a novel Porcine Reproducti

其他学术论文