Tempo Combine Treatment with Hyperthermia Switch the Cell Death from Apoptosis to Autophagy

来源 :2014第七届世界癌症大会 | 被引量 : 0次 | 上传用户:xie2372
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  Heat stress or a superoxide disrnutase mimic nitroxide, Tempo, induces apoptosis, while their combination causes non-apoptotic cell death.However, the mechanism for this switch remains unclear.In this study, we identified that Tempo combine treatment with hypertherrnia rapidly induced autophagic cell death in U937 and HeLa cells.
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