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目的:探讨中药对急性过敏性紫癜(Henochschonleinpurpura,HSP)免疫功能的调节作用。方法:将100例HSP患儿按1∶1分为中药治疗组(中药组)和西药治疗组(西药组),观察两组患儿治疗后疗效,检测两组病例治疗前后T细胞亚群CD3、CD4、CD8、CD4/CD8比值和免疫球蛋白IgG、IgA、IgM水平,并进行比较。结果:中药组疗效优于西药组,复发率低于西药组;对HSP患儿免疫功能的调节作用,中药组优于西药组。结论:中药能调节HSP患儿的免疫功能,能缩短HSP患儿的症状持续时间,降低HSP患儿的复发率。
Objective: To investigate the regulatory effect of traditional Chinese medicine (TCM) on immune function in Henoch-Schonlein Purpura (HSP). Methods: One hundred and fifty children with HSP were divided into TCM treatment group (TCM group) and western medicine treatment group (Western medicine group) by 1: 1. The curative effect of two groups of children after treatment was observed. T cell subsets CD3 , CD4, CD8, CD4 / CD8 ratio and immunoglobulin IgG, IgA, IgM levels, and compared. Results: The curative effect of traditional Chinese medicine group was better than that of western medicine group, the recurrence rate was lower than that of Western medicine group. The immune function of HSP group was better than Western medicine group. Conclusion: Chinese medicine can regulate the immune function of children with HSP, can shorten the duration of symptoms in children with HSP and reduce the recurrence rate of children with HSP.