Effect of oxygen supply on the intracellular flux distribution and a two-stage OUR control strategy

• 作 者: KangKangPing[1]ZeJianWang[1]FeiLu[1]WeiZhao[2]JuChu[1]YingPingZhuang[1]YongHongWang[1]
• 机 构: State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Sha
• 出 处: 2015年上海市研究生学术论坛(生物化工)
• 发表日期: 2015年期

　　Backgrounds: In this study, the performance of aerobic batch fermentation with Aspergillus niger producing sodium gluconate under different oxygen supply levels through adjusting the agitation rate were investigated.The response of glucose metabolism in A.niger to different oxygen uptake rate (OUR) levels has been studied in the present work.