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Purpose: The aim of this study is to evaluate the stability zygoma implant with remaining teeth in supporting a prosthesis for subjects who had undergone hemi-maxillectomy.Methods: Ten patients were included in the study.Oral rehabilitations were performed with temporary prosthesis supported by remaining teeth for the first three months.The final prosthesis will be supported by remaining teeth and zygoma implant,prosthesis was tailored made according to biomechanical three-dimensional finite element analysis result.The patients were assessed by referring to prosthesis functioning scale(OFS)of the Memorial Sloan-Kettering Cancer Center.In addition,the retention and bite force were recorded with temporary prosthesis and final prosthesis respectively.Conclusion: The bite force was increased significantly with the support of zygoma implant.The application of zygoma implant in the restoration of maxillary defects showed good results in functional outcome and social acceptance.