Objective: The research is to study the cell proliferation and apoptosis and autophagyin renal cell carcinoma cells influence by the PI3K/AKT/mTor inhibitor NVPBEZ235.Looking for a new treatment strat
Objective: To study the clinical effect of combined kidney transplantation and splenic fossa auxiliary heterotopic liver transplantation to treat highly sensitized recipients.Methods: Combined kidney
Objective: To investigate the relationship between mitochondrial DNA (mtDNA) copy number in peripheral blood leukocytes (PBLs) and the risk and the prognosis of prostate cancer (PCa).Methods: In a cas
Protein phosphatase 1, regulatory subunit 13 like PPP1R13L, also coined iASPP, was found high expression in prostate cancer tissues and cell lines.In previous research, in vitro and in vivo RNAi media
Purpose: In order to anatomically reconstruct the ureteral stenosis, we present a novel technique for laparoscopic ureteral reimplantation.Patients and methods: Three young females, who were diagnosed
Background: A functional-94 insertion/deletion polymorphism (rs28362491) in the promoter of the NFKB1 gene was reported to influence NFKB1 expression and confer susceptibility to different types of ca
目的:探讨缺氧诱导因子-1α(HIF-1α)在肾癌组织中表达及其与Bcl-2和PCNA的关系,了解肿瘤增殖与凋亡的特点.方法:采用免疫组织化学方法检测61例肾癌石蜡标本切片HIF-1α、Bc1-2和PCNA的表达.结果:HIF-1α在肾癌组织中阳性率为57.4％(35/61),其表达与不同临床分期、病理分级有关(P＜0.05),与组织学分类无关(P＞0.05).Bcl-2在肾癌组织中阳性率为42.
目的:探讨体质指数(BMI)、腰臀比(WHR)与男性精子质量的关系.方法:选择80例男性,测量其身高、体重、腰围、臀围,计算体质指数和臀腰比,按WHO第五版标准,进行计算机辅助精子动态,分析BMI和臀腰比与精子质量参数的关系.结果:BMI与a级精子数(r=0.374,P＜0.01)有显著正相关性,与精子总数呈显著的负相关(r=-0.297,p＜0.05),与精子活力无显著相关性(P＞0.05).臀
肾内科和内分泌科医生共同思考的问题:·为什么2型糖尿病患者只有30％左右最后出现糖尿病肾病或进入透析治疗?肾脏超微结构的个体差异·王海燕肾脏病学:人类双侧肾小球数量23-180万个·近些年尸体解剖的数据提示新生儿固有肾小球数量个体差异非常大(数倍到十数倍)·美国在越南战争和朝鲜战争阵亡士兵上千例尸检也证明,个体肾小球数量差异可达到10倍甚至更多.·肾小球和肾小管功能缺陷(先天遗传)·肾脏小血管病变
基本概念常指合并有复杂因素的尿感:临床治愈率低,且伴持续性菌尿或反复发作者;复杂因素通常包括:尿路梗阻(先天、继发及医源性)、尿路器械使用、糖尿病等代谢疾病、激素水平变化、邻近器官感染、致病菌谱变化及耐药性产生等