Down-regulated RFX1 promotes TH-17 differentiation in Lupus through Epigenetic Changes

来源 :2015 International Symposium on Epigenetics and Autoimmunity | 被引量 : 0次 | 上传用户：ghostbyte

【摘要】

：

　　Aberrant activation and differentiation of CD4+ T cells into Thl7 cells is one of key immunological changes in the development of systemic lupus erythematos

【作者】

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Ming Zhao Qianjin Lu

【机构】

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DepartmentofDermatology,TheSecondXiangyaHospital,CentralSouthUniversity,HunanKeyLaboratoryofMedicalE

【出处】

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2015 International Symposium on Epigenetics and Autoimmunity

【发表日期】

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2015年4期

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　　Aberrant activation and differentiation of CD4+ T cells into Thl7 cells is one of key immunological changes in the development of systemic lupus erythematosus (SLE).However, the mechanisms remainspoorly understood.

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Down-regulated RFX1 promotes TH-17 differentiation in Lupus through Epigenetic Changes

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