Ultrastructural dissection of neuronal synapses using cryo electron tomography

来源 :第四届全国冷冻电子显微学与结构生物学专题研讨会 | 被引量 : 0次 | 上传用户：yeshen

【摘要】

：

Neuronal synapses are key communication devices in brain circuits.Within the synapse,various subcellular components form highly ordered yet dynamic structure to

【作者】

：

Guoqiang Bi

【机构】

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CenterforIntegrativeImaging,HefeiNationalLaboratoryforPhysicalSciencesattheMicroscale,andSchoolofLif

【出处】

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第四届全国冷冻电子显微学与结构生物学专题研讨会

【发表日期】

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2015年6期

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Neuronal synapses are key communication devices in brain circuits.Within the synapse,various subcellular components form highly ordered yet dynamic structure to carry out critical functions of information transmission and storage.Using cryo electron tomography as well as correlative fluorescence light and electron microscopy,we visualized in situ organization of macromolecules and organelles of various synapses in intact hippocampal neurons grown in culture.

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Ultrastructural dissection of neuronal synapses using cryo electron tomography

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