• 不 限
  • 期刊论文
  • 硕博论文
  • 会议论文
  • 报 纸
  • 英文论文
  2. 您的位置
  3. 首页
  4. 会议论文
  5. Therapeutic targetting of endothelin and nitric oxide In hypertension and chronic kidney disease

Therapeutic targetting of endothelin and nitric oxide In hypertension and chronic kidney disease

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户：miclleg
【摘 要】
：
Chronic kidney disease (CKD) is a common and growing public health problem,strongly associated with high blood pressure (BP), and causing substantial cardiovascular mortality and morbidity.CKD is also
【作 者】
：
David J WEBB 
【机 构】
：
British Pharmacological Society and Vascular Biology Group,BHF Centre of Research Excellence,Queen'
【出 处】
：
The 12th Meeting of the Asia Pacific Federation of Pharmacol
【发表日期】
：
2013年4期
下载到本地 , 更方便阅读
下载此文 赞助VIP
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Chronic kidney disease (CKD) is a common and growing public health problem,strongly associated with high blood pressure (BP), and causing substantial cardiovascular mortality and morbidity.CKD is also associated with endothelial dysfunction and arterial stiffness, independent predictors of poor outcome.
其他文献
4-Acetylantroquinonol B isolated from Antrodia cinnamomea inhibited prostate cancer cells growth and
Aim: The 4-acetylantroquinonol B (4AAQB) isolated from the mycelium of Antrodia camphorata could inhibit proliferation of hepatocellular carcinoma cells HepG2 with very low IC50.However, the detail mo
会议
4AAQBprostate cancerproliferationmetastasis
Anticancer effects of Gekko ethanol extract In human hepatocellular carcinoma HepG2 cells and In H22
Aim: To explore the anticancer effects and underlying mechanism of Gekko ethanol extract (GEE) in vitro and in vivo.Methods: MTT assay was employed to evaluate the anti-proliferative effect of GEE in
会议
Gekko ethanol extractapoptosisantiangiogenesishepatocellular cancer
Potentiating effect of citral on anticancer activities of doxorubicin, vincristine, and etoposide In
Aim: Citral is a mixture of terpene aldehydes in essential oils of several plants used for cooking such as lemongrass.This study intended to evaluate the potentiating effect of citral on anticancer ac
会议
citralanticancerhuman B-lymphoma Ramos cells
Oleanolic acid regulates LOX-1/NADPH/ROS pathway inhibiting ox-LDL induced injury in HUVECs cells
Aim: To investigate the effect and possible mechanisms of oleanolic acid (OA) in preventing endothelial cell oxidative injury induced by human high oxidized low-density lipoprotein (h ox-LDL).Methods:
会议
oleanolic acidLOX-1NADPH oxidaseoxidized low density lipoproteinHUVEC
Differential protein expression of plumbagin treated CCA cell line
Aim: Medicinal plant extracts are alternative sources of promising anti-cancer compound such as Plumbago extracts.Therefore, this study aims to investigate the effect of plumbagin on protein expressio
会议
plumbagincholangiocarcinomaprotein expressionLC-MS/MS
12-0-tetradecanoylphorbol-13-acetate increases sensitibity of cisplatin to human lung adenocarcinoma
Aim: To investigate whether 12-O-tetradecanoylphorbol-13-acetate (TPA) can increase the sensitivity of cisplatin on human lung adenocarcinoma cisplatinsensitive cell line A549 and cisplatin-resistant
会议
12-O-tetradecanoylphorbol-13-acetate (TPA)cisplatinlung adenocarcinoma cellsN
Novel hydrogen sulfide releasing derivatives of 3-n-Butylphthallde attenuate ischemic brain damage i
Aim: NBP was employed as the lead compound to obtain a novel class of H2Sreleasing derivatives.We investigated their antiplatelet activity in vitro and antiischemic stroke activity in vivo, and addres
会议
3-n-butylphthalide derivativeantiplatelet activitycerebral ischemiaMCAONOX4
The stability of NR2B In the nucleus accumbens controls behavioral and synaptic adaptations to chron
Aim: The nucleus accumbens (NAc) is closely correlated with psychiatric disorder.It has been demonstrated that the glutamatergic system in NAc plays an important role in the reward pathway.We therefor
会议
nucleus accumbensNR2Bsynaptic plasticitychronic stressamphetamine
Regulation of cell functions by Ca2+: from basic principles to therapeutic targets
Intracellular Ca2+ signaling regulates numerous cell functions including contraction,secretion, and immune responses.There are many potential molecular targets for drug development in conjunction with
会议
High level expression of anti-TNF-α monoclonal antibody in CHO/DHFR-cells
Aim: TNF-α has been proved as a therapeutic target for rheumatoid arthritis.However, the cost of anti-TNF-α biologic agents is considerable and unacceptable at present.Here, a high level expression sy
会议
rheumatoid arthritisanti-TNF-α mcAbCHO/DHFR-cellbicistronic expression