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  5. Novel hydrogen sulfide releasing derivatives of 3-n-Butylphthallde attenuate ischemic brain damage i

Novel hydrogen sulfide releasing derivatives of 3-n-Butylphthallde attenuate ischemic brain damage i

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户：ktzgy
【摘 要】
：
Aim: NBP was employed as the lead compound to obtain a novel class of H2Sreleasing derivatives.We investigated their antiplatelet activity in vitro and antiischemic stroke activity in vivo, and addres
【作 者】
：
Lin-na WANG Ting-ting LI Hui JI 
【机 构】
：
Department of Pharmacology, China Pharmaceutical University, Nanjing 210009, China
【出 处】
：
The 12th Meeting of the Asia Pacific Federation of Pharmacol
【发表日期】
：
2013年4期
【关键词】
：
3-n-butylphthalide derivative antiplatelet activity cerebral ischemia MCAO NOX4 
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Aim: NBP was employed as the lead compound to obtain a novel class of H2Sreleasing derivatives.We investigated their antiplatelet activity in vitro and antiischemic stroke activity in vivo, and addressed the mechanisms that contributed to the neuroprotective effects.
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