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Positron emission tomography (PET) has been proven to be a powerful tool in both clinical diagnosis and biomedical research.However, limited by the traditional analog-based electronics and closed system architecture, there is still much room for improvement for PET systems.In this presentation, we will introduce Trans-PET(R)-the worlds first all-digital PET system.With a number of unique patented all-digital technologies, Trans-PET(R) avoids high operation/maintenance cost and complex operation/correction, which are common in traditional analog-based PET system.