【摘 要】
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Next generation sequencing technologies transformed biology into big data science.Our lab coordinated and participated de novo genome sequencing as well as carr
【机 构】
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AgriculturalGenomeInstituteatShenzhen,ChineseAcademyofAgriculturalSciences(CAAS),Shenzhen518124,Chin
论文部分内容阅读
Next generation sequencing technologies transformed biology into big data science.Our lab coordinated and participated de novo genome sequencing as well as carried out population resequencing and transcriptome sequencing of several major vegetable crops,including cucumber,tomato,and potato.In total,we generated 20 Tbps(2×1013 bps) genomic data in the past few years.We combined this big data with molecular biology and biochemistry to discover the mechanisms of several biological and evolutionary processes,including domestication of cucumber and tomato,sex determination and tendril development in cucumber.These studies enable a molecular design of a cucumber genotype with bitter foliage for insect resistance and nonbitter fruits even under stress.Furthermore,we will share our vision to re-domesticate potato using genomics,transforming the tuber-propagated autopolyploid that is difficult for breeding,into a breeder-and environment-friendly crop that is a diploid and propagated by true seeds.
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