NAMPT Inhibitor FK866 as a Potent Molecule to Promote DrugSensitivity to Temozolomide in Glioma Cell

来源 :中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议 | 被引量 : 0次 | 上传用户：fengwei27149

【摘要】

：

Glioma is a primary brain tumor with most prevalence and poor prognosis.Temozolomide(TMZ) is the firstline chemotherapy drug to treat glioma patients post surgery.However, the failure of chemotherapy

【作者】

：

王培银李明眏周文科金保哲张晨光江涛张新中丁卫

【机构】

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Department of Neurosurgery, The First Affiliated Hospital of Xinxiang Medical University, Xinxiang M

【出处】

：

中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议

【发表日期】

：

2014年3期

【关键词】

：

FK866 NAMPT Glioma TMZ Chemotherapy

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　　Glioma is a primary brain tumor with most prevalence and poor prognosis.Temozolomide(TMZ) is the firstline chemotherapy drug to treat glioma patients post surgery.However, the failure of chemotherapy is often seen due to the development of tumorcell resistance to the cytotoxic effects of TMZ.

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NAMPT Inhibitor FK866 as a Potent Molecule to Promote DrugSensitivity to Temozolomide in Glioma Cell

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