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  5. Knockdown of PKM2 induces the compensation of glutaminolysis through □-catenin-Myc pathway in tumor

Knockdown of PKM2 induces the compensation of glutaminolysis through □-catenin-Myc pathway in tumor

来源 :中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议 | 被引量 : 0次 | 上传用户：xiaotian521
【摘 要】
：
Tumor cells undergo glycolysis even in the presence of oxygen, consuming large amountsof glucose and ultimately generating lactic acid.This phenomenon is defined as the Warburgeffect.In addition, tumo
【作 者】
：
武海丽 李宗伟 杨鹏 李卓玉 
【机 构】
：
山西大学生物技术研究所
【出 处】
：
中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议
【发表日期】
：
2014年3期
【关键词】
：
M2-type pyruvate kinase compensation glutaminolysis miR-200a β-catenin/c-Myc 
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Tumor cells undergo glycolysis even in the presence of oxygen, consuming large amountsof glucose and ultimately generating lactic acid.This phenomenon is defined as the Warburgeffect.In addition, tumor cells also exhibit excessive addition to glutamine.
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