Water-solublefullerenes,C60[N(CH2)2OH]12,C60[N(CH2)2NH2]10,and C60[N(CH2)2COOH]10,were synthesized by improved nitrene chemistry[1],which C60 was reacted with azide small molecules(N3(CH2)2OH,N3(CH2)2
rtTA(reverse tetracycline-controlled transactivator) and TRE(Tetracycline Responsive Element) will bind to each other under the action of tetracycline and form one complex.When this complex passes thr
Mesoporous silica nanoparticles(MSNs)are a promising material for drug delivery.We delicately prepared a mesoporous silica nanoparticle(MSN)for the delivery of low water solubility drug to tumor cells
Despite the significant advantages of nano-micellar systems on drug delivery,the poor therapeutic outcome in clinic is ascribed to inefficient tumor uptake and poor intracellular drug release.Plumbagi
The combination of doxorubicin(DOX)with sorafenib(SOR)has been proved to be an effective strategy to enhance anti-hepatocellular carcinoma(HCC)efficiency [1].However,respective in vivo pharmacokinetic
Ursolic Acid(UA)is natural compound which has been shown to possess wide range of pharmacological activities including anti-inflammatory,anti-cancer,anti-oxidant and anti-microbial effects,but its bio
Circulating tumor cells (CTCs) were considered to be preconditions for the metastasis and recurrence of cancer.We hypothesized that adhesion of CTCs to vascular endothelial bed might be a crucial star
Targeted delivery of therapeutic nanoparticles have shown a significant feature in disease-specific manner compared with non-target nanoparticles.We have developed NPs formulated with poly(D,L-lactic-
Terahertz (THz) wave has numerous applications due to its capabilities of penetrating many materials such as plastic,clothes,woods,ceramic,rubber and so on,and characteristic spectra of chemicals,drug
Cancer is a term used for diseases in which abnormal cells divide without control and are able to invade other tissues.According to the World Health Organization,cancer is a leading cause of death and