高脂饮食诱导肥胖小鼠心脏、胰腺及肝肾组织黑皮质素受体-4的表达

来源 :中华医学会第十二次全国内分泌学学术会议 | 被引量 : 0次 | 上传用户：daxiang11

【摘要】

：

目的:研究黑皮质素受体-4(MC4R)在心脏、胰腺及肝肾组织的表达及高脂饮食对MC4R表达的影响.方法:选取雄性健康野生型C57/BL6小鼠12只,随机分为两组,分别给予普通饲料(对照组)和高脂饲料(造模组)喂养12周.测定体重、血糖和血胰岛素.实时荧光定量PCR法测定心脏、胰腺和肝肾组织MC4R相对表达量.

【作者】

：

赵苇苇乔晓娜张烁鹿斌叶红英胡仁明周丽诺李益明杨叶虹

【机构】

：

复旦大学附属华山医院内分泌科 200040

【出处】

：

中华医学会第十二次全国内分泌学学术会议

【发表日期】

：

2013年7期

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高脂饮食诱导肥胖小鼠心脏、胰腺及肝肾组织黑皮质素受体-4的表达

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