In mammals, oocytes within the primordial follicles require a number of essential factors to maintain their survival.However, the survival factors for activated
Trichloroethylene (TCE) is ubiquitous in our living environment as a contaminant in air, water and food.Prenatal exposure to TCE is reported to cause congenital
Acrylamide (ACR) is a compound with severe neurotoxicity, genotoxicity, carcinogenicity and reproductive toxicity.Recent studies show that ACR impairs the funct
Major depressive disorder (MDD) is diagnosed by subjective clinical evaluation,leading to underdiagnosis and misdiagnosis.Statedependent biomarkers for MDD woul
Anti-platelet treatment is of fundamental importance in combatting functions/dysfunction of platelets in the pathogenesis of cardiovascular and inflammatory dis
The eleven human histone deacetylases (HDACs) are essential epigenetic regulators of gene transcription,functioning throughspatial-temporal recruitment of prote
Colorectal cancer is the fourth most common cause of cancer deaths worldwide and the high mortality rate is mostly ascribed to liver metastasis.Unfortunately,wi
Proteomics has recently promised delivery of more comprehensive membrane proteome coverage.Recent shotgun proteomics studies on colorectal cancer (CRC) cell lin
The talk oversees a short but eventful history of Orbitrap mass spectrometry,from laying down the first principles to its current status in mainstream mass spec