Depression is highly prevalent in individuals with diabetes and the depressive symptoms are less responsive to current antidepressant therapies.Oxidative stress plays a major role in both the pathogen
Long-term depression of inhibitory responses (LTD),as mediated by endocannabinoid (eCB),plays an important role on presynaptic plasticity in the mammalian brain.However,the involvement of eCB on the d
Formaldehyde (FA) has neurotoxicity and we have previously demonstrated that hydrogen sulfide (H2S),the third gasotransmitter,antagonizes FA-induced neurotoxicity.However,the exact mechanisms underlyi
Fear conditioning is an associative learning in which a conditioned neutral stimulus is paired with an aversive unconditioned stimulus to elicit fear response.Repeated exposures to conditioned stimulu
Cell-type specific differences in the kinetics of inhibitory postsynaptic conductances (IPSCs) impact upon network dynamics throughout the brain.Much attention has been focused on how GABAA receptor a
The investigation of mitochondrial abnormalities in brain commonly requires isolation of these organelles.Methods for isolating brain mitochondria rarely rely solely on differential centrifugation as
Objective:Increasing evidences have shown that subtle factors in parents can influence long-term health in their offspring.Although the impacts of exercise-induced maternal development on fetal size a
Aim:This study was designed to investigate rhythmic expression of NCX1 and circadian clock genes as well as their interference in either cultured HL-1 cells or fresh isolated neonatal rat ventricular