Blocking neurodegenerative damages of Alzheimer's disease by aromatic glycosides in multiple pa

来源 :微循环国际研讨会暨第十三届全国中西医结合微循环学术会议(International Conference for Mic | 被引量 : 0次 | 上传用户:k1165445191
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Blocking neurodegeneration of Alzheimers diseases is global puzzles in medicine.Single blocking either oxidative stress or inflammation is not ideal strategy for this complicated illness.Through our studies, we found some of phenolic glycosides (Xy-B-25, Xy-B-23,BL-B-14, BL-E-8, SCI-Et-18, SC2-19 and IO-B-40) present significant inhibition on cortical neuronal death induced by Aβ1-42.Simultaneously, the endogenous ROS, biomarker of DNA,lipid and protein damages were all reduced dramatically.
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