G-QUADRUPLEX相关论文
富G碱基的DNA序列在离子诱导下可形成G-四链体(G4),基于这一构型转化设计了大量的传感检测平台.其中的荧光检测平台是基于G4与荧光......
固定化酶相较于游离的酶有贮存稳定性高、活力强、回收易等一系列优点。因此,人们很早之前就对酶的固定化展开了研究。最开始是单......
DNA酶中的G-四链体-血红素(G4-hemin)DNA酶结构具有较高的设计性和化学稳定性,因此格外受研究者关注.G-平面作为辅酶因子hemin的结......
A novel aptasensor strategy for protein detection based on G-quadruplex and exonuclease Ⅲ-aided recy
The detection of biomarkers is of great significance in the diagnosis of numerous diseases, especially cancer. Herein, w......
How G-quadruplex topology and loop sequences affect optical properties of DNA-templated silver nanoc
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的:寻找具有阳离子型卟啉结构的强效端粒酶抑制剂.方法:采用Adler-Longo卟啉合成法通过芳香醛和吡咯的缩合反应制得各种组合的3-......
The DNA G-quadruplex formed by the human telomeric sequence is a potential target for novel anticancer drugs. We have in......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
In this research, an unusually dimeric G-quadruplex of d(GGGTGGGTGGGTGGGT) (Sl), the potent nanomolar HIV-1 integrase in......
The G-quadruplexes formed from G-rich strands in the telomere and oncogene-promoter regions are regarded as new promisin......
