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  5. Investigation of formation of dimeric G-quadruplex of HIV-1 integrase inhibitor by nuclear magnetic

Investigation of formation of dimeric G-quadruplex of HIV-1 integrase inhibitor by nuclear magnetic

来源 :中国化学快报（英文版） | 被引量 : 0次 | 上传用户：treesoft_ng
【摘 要】
：
In this research, an unusually dimeric G-quadruplex of d(GGGTGGGTGGGTGGGT) (Sl), the potent nanomolar HIV-1 integrase inhibitor, was detected by nuclear magneti
【作 者】
：
Hui Hui Li Gu Yuan 
【机 构】
：
Beijing National Laboratory for Molecular Sciences
【出 处】
：
中国化学快报（英文版）
【发表日期】
：
2004年期
【关键词】
：
G-quadruplex HIV-I integrase inhibitor Nuclear magnetic resonance 
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In this research, an unusually dimeric G-quadruplex of d(GGGTGGGTGGGTGGGT) (Sl), the potent nanomolar HIV-1 integrase inhibitor, was detected by nuclear magnetic resonance (NMR). This result has been confirmed by electrospray ionization mass spectrometry (ESI-MS) and circular dichroism (CD).
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