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目的：建立拆分萘普生对映体的方法。方法：采用超临界流体色谱法。以萘普生对映体的分离时间、容量因子、分离因子、分离度为考察指标......

In Korea and China, ilaprazole is a widely used proton pump inhibitor in the treatment of gastric ulcers. In this study,......

Ibuprofen is widely used as a non-steroidal anti-inflammatory drug and produced as racemic mixture. Its pharmacological ......

The protein binding of non-steroidal anti-inflammatory drugs flurbiprofen, ketoprofen and etodolac with human serum albu......

建立了高效液相色谱法同时测定盐酸达卡他韦及其5个光学异构体。采用Chiralpak IC色谱柱,以甲基叔丁醚(含0.1%二乙胺)∶甲醇(88∶1......

本文通过对荣华二采区10...

目的采用手性固定相高效液相色谱法拆分异丙肾上腺素对映体。方法以氯甲酸苄酯作为非手性衍生化试剂,与异丙肾上腺素进行衍生化反......

为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......

目的 研究不同甲氨蝶呤(MTX)对映体耐药与叶酰聚谷氨酸合成酶(FPGS)基因水平表达的关系.方法 用大剂量冲击递增结合低剂量持续诱导......

Distribution behavior of ketoprofen enantiomers was examined in methanol aqueous and organic solvent mixture containing ......

目的:建立酮洛芬对映异构体的拆分方法。方法:采用柱前衍生化RP-HPLC法,以L-丙氨酸-β-萘胺(L-Ala-β-NA)为手性衍生化试剂,色谱柱......

Two new chiral stationary phases, 2,3-di-O-acetyl-6-O-trimethylsilyl-β-cyclodextrin (DATBCD)and 2, 6-di-O-trimethylsily......

建立直接拆分氨氯地平对映体的HPLC方法,并用于其含量测定.以CHIRALPAK AD-H为固定相,在正相条件下考察了流动相组成、流速、柱温......

建立了液相色谱-串联质谱(LC-MS/MS)法测定犬血浆中的泮托拉唑(1)对映异构体,并应用于1在Beagle犬体内立体选择性药动学研究。采用......

The protein binding of non-steroidal anti-inflammatory drugs flurbiprofen,ketoprofen and etodolac with human serum album......

Erythromycin as a new chiral selector was first used for chrial separation of four derivatives of biphenyldimethylester ......

Starting from shikimic acid, the total synthesis of zeylenone was studied. The product was proved to be the (+)antipode ......

Many of the drugs currently used in medical practice are racernates.The enantiomers of a racemic drug differ in pharrnac......