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目的研究医院感染对急性心肌梗死患者生存质量及体液免疫状态的影响,以进一步了解医院感染对急性心肌梗死患者的不良影响。方法选取2014年4月-2016年7月期间的70例急性心肌梗死并发医院感染患者为A组,70例心肌梗死无医院感染患者为B组,70名体检健康同龄者为C组,将三组研究对象的生存质量及体液免疫指标进行评估、检测及比较,并比较A组中不同感染部位患者的评估与检测结果。结果 A组的世界卫生组织生存质量测定量表简表(WHOQOL-BREF量表)心理状态、生理状态、环境领域及社会关系评分分别为(49.20±4.84)分、(41.35±4.66)分、(44.98±3.67)分及(39.88±4.20)分,均低于B组的(59.17±5.23)分、(50.21±5.32)分、(53.63±4.41)分、(51.35±5.26)分及C组的(72.53±5.73)分、(73.63±6.18)分、(68.46±4.97)分、(78.56±6.43)分,B组评分则低于C组,同时A组的体液免疫指标均低于B组及C组,B组则低于C组(P<0.05),而A组中不同感染部位患者的生存质量评分及体液免疫指标则无明显差异。结论医院感染对急性心肌梗死患者生存质量及体液免疫状态的不良影响较为突出,因此认为对于急性心肌梗死患者尤其应重视医院感染的防控与诊治。
Objective To study the influence of nosocomial infection on the quality of life and humoral immune status of patients with acute myocardial infarction in order to further understand the adverse effects of nosocomial infection on patients with acute myocardial infarction. Methods A total of 70 patients with acute myocardial infarction complicated by nosocomial infection were selected as Group A from April 2014 to July 2016, 70 patients with myocardial infarction without hospital infection were selected as Group B, 70 healthy people of the same age as Group C, The quality of life and humoral immunity indexes of the study group were evaluated, compared and tested, and the results of evaluation and test in patients with different infection sites in group A were compared. Results The scores of WHOQOL-BREF scales in group A were (49.20 ± 4.84) points and (41.35 ± 4.66) points respectively, ( 44.98 ± 3.67, and 39.88 ± 4.20, respectively, which were lower than those in group B (59.17 ± 5.23), (50.21 ± 5.32), (53.63 ± 4.41), (51.35 ± 5.26) (72.53 ± 5.73) points, (73.63 ± 6.18) points, (68.46 ± 4.97) points and (78.56 ± 6.43) points respectively. The score of B group was lower than that of C group, while the humoral immunity index of A group was lower than that of B group Group C and group B were lower than group C (P <0.05), while there was no significant difference in quality of life score and humoral immunity among patients with different infection sites in group A. Conclusions The nosocomial infection has a significant impact on the quality of life and humoral immunity of patients with acute myocardial infarction. Therefore, it is considered that the prevention and treatment of nosocomial infections should be emphasized in patients with acute myocardial infarction.