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本实验证实稀土动力学特点是:稀土从血液向机体输入的速度快且量也多,而反分布速度慢且量也少,同时从机体清除的量也少。表明稀土在体内有蓄积,并证实脾肝是稀土重要蓄积器官,在骨内蓄积并不明显。经口染毒产生有害影响很小。目前我国稀土工业化生产已进入新的阶段,随之而来在工农业生产上应用更加广泛,接触者越来越多。为了保护工人和居民的健康,国内不少单位对其毒性作了很多研究,但稀土对灵长类大动物的毒性报道尚不多见,猴子的生物学特性与人类相似,本实验给恒河猴用静脉注射,灌胃及90天喂饲稀土法,观察其在动物体内的吸收,分布与排泄。
This experiment confirmed that rare earth kinetics is characterized by: rare earth input from the blood to the body faster and more, and anti-distribution slow and the amount of less, while the amount of clearance from the body less. It shows that there is accumulation of rare earth in the body, and confirmed that spleen and liver are important organs of rare earth accumulation in the bone accumulation is not obvious. Oral exposure produces little harmful effects. At present, China’s rare earth industrial production has entered a new phase, followed by industrial and agricultural production is more widely used, more and more contacts. In order to protect the health of workers and residents, many domestic units made a lot of studies on their toxicity, but rare earth toxic reports on primates are rare, and their biological characteristics are similar to those of humans. In this study, Monkey with intravenous, intragastric feeding and 90 days feeding rare earth method to observe its absorption, distribution and excretion in animals.