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用速率散射比浊法检测56例糖尿病患者血清铜蓝蛋白(CER)、α_1-酸性糖蛋白(AAG)和α_1-抗胰蛋白酶(AAT)含量,并与正常对照组进行了比较。结果表明,糖尿病患者血清CER、AAG含量明显高于正常对照组,但AAT含量却明显低于正常对照组。糖尿病伴视网膜病变组血清CER、AAG含量明显高于无视网膜病变组,AAT含量却明显低于无视网膜病变组。检测糖尿病患者血清CER、AAG和AAT含量,与微血管病变关系有一定临床意义。
The contents of ceruloplasmin (cer), α 1-acid glycoprotein (AAG) and α 1-antitrypsin (AAT) in 56 patients with diabetes mellitus were detected by rate nephelometry and compared with the normal control group. The results showed that the serum levels of CER and AAG in diabetic patients were significantly higher than those in normal controls, but the AAT levels were significantly lower than those in normal controls. The serum levels of CER and AAG in diabetic patients with retinopathy were significantly higher than those without retinopathy, but the contents of AAT in diabetic patients with retinopathy were significantly lower than those without retinopathy. Detecting the serum of patients with diabetes CER, AAG and AAT content, and microvascular disease has some clinical significance.