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合成了新颖的多功能试剂4-(叔丁基二甲基硅烷酮)苯甲酸.利用其可偶合多种生物分子中的—NH和—OH基团,设计一种作为光亲和探针的生物分子功能化的通用方法,并讨论了鉴定镰刀型细胞贫血症受体靶点的潜在应用.
A novel multifunctional reagent, 4- (tert-butyldimethylsilanone) benzoate, was synthesized.It can be used to couple a series of biomolecules with -NH and -OH groups to design a A general approach to functionalization of biomolecules and discusses the potential use of identifying sickle cell anemia receptor targets.