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中药雷公藤被鉴为“中药激素”,临床治疗疾病种类日趋增多。由于该药可损伤动物睾丸生精上皮细胞,导致实验动物不育,已引起了计划生育工作者和临床医师密切注意本研究所用25份精液标本,皆采自服该药的强直性脊拄炎患者,年令在19～32岁间。服约3日内,精子密度变化不明显、活力下降:服药60日内,精子密度明显下降,活力下降至零;超过60日,精子密度均为零。1例服药9个月,停药9个月之精液,活力为Ⅲ级,密度为136×10~6/ml。超微结构显示:残留
Chinese medicine Tripterygium has been identified as “traditional Chinese medicine hormone”, clinical treatment of disease types are increasing. As the drug can damage animal testicular germ epithelial cells, resulting in sterility of experimental animals, has caused family planning workers and clinicians pay close attention to 25 sperm specimens used in this study, all taken from the medication of ankylosing myelitis Patients, the year 19 to 32 years old. Serve about 3 days, the sperm density changes were not obvious, decreased vitality: medication within 60 days, sperm density decreased significantly, vitality decreased to zero; more than 60 days, sperm density are zero. One patient took medicine for 9 months and stopped taking drug for 9 months. The activity was grade Ⅲ and the density was 136 × 10 ~ 6 / ml. Ultrastructural display: residual