创伤性脑损伤研究新进展

• 作 者: 栾樱译 姚咏明
• 出 处: 国际外科学杂志
• 发表日期: 2021年1期
• 关键词: 脑损伤 治疗应用 创伤性脑损伤 调控机制 监测

创伤性脑损伤(TBI)病情进展迅速、预后险恶，给临床救治工作带来极大困难，已成为现代急危重症医学面临的突出难题。除了特殊情况下必要的手术干预外，有关TBI的临床处置措施、无创和有创监测模式等近年来有了新的认识。本文重点阐述了TBI的监测和治疗现状，通过对TBI病理生理机制的深入了解，在发病不同环节采取针对性和精准化策略干预，同时持续监测各项指标动态变化，最终防止组织及器官的继发性损伤，达到降低急危重症患者伤残率和病死率之目的。“,”With rapid progress and dangerous prognosis, traumatic brain injury (TBI) brings great difficulties in the clinical treatment, which becomes a prominent problem for the modern emergency and critical care medicine. In addition to the necessary surgical intervention under special circumstances, there are new understandings about the clinical management measures, noninvasive and invasive monitoring mode of TBI in recent years. This review provides a summary of the monitoring and treatment on the TBI, with our deep understanding of regulatory mechanism underlying TBI, precise modulation might be of clinical significance in preventing secondary damage of tissues and organs, which would be associated with decreases in the disability and mortality of critically ill patients.