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目的探讨CT联合血清肿瘤标志物检测对早期肺癌的临床诊断价值。方法回顾性分析我院于2005年1月~2007年6月来我院查体的150例初筛为肺癌高危人群的受检者的临床资料,根据CT表现分为高危组、中危组、低危组,每组各50人,三组均检测血清肿瘤标志物,中、高危组对检测有阳性指标者进行病理学检查,低危组及多项肿瘤标志物均阴性者或拒绝行病理检查者进行为期1~5年的跟踪随访,比较各组间各项指标的差异性。结果中、高危组共确诊47例肺癌,其中肿瘤标志物均为阳性者28例,约占59.6%,低危组及各项肿瘤标志物检测均为阴性者共52例,经随访后做病理确诊为肺癌2例,约占3.8%,与中、高危组相比较具有统计学意义(P<0.05)。结论 CT联合血清肿瘤标志物检测可以提高早期肺癌诊断的准确率,具有重要的临床意义。
Objective To investigate the clinical value of CT combined with serum tumor markers in the diagnosis of early stage lung cancer. Methods A retrospective analysis of our hospital from January 2005 to June 2007 to our hospital physical examination of 150 cases of primary screening for high-risk groups of lung cancer subjects clinical data, divided into high-risk group based on CT, the risk group, Low-risk group, each group of 50 people, three groups were detected serum tumor markers, medium and high-risk group of patients with positive indicators for pathological examination, low-risk group and a number of tumor markers were negative or reject the pathology Inspector for a period of 1 to 5 years follow-up, comparison of the various indicators of the differences between groups. Results, a total of 47 cases of high-risk lung cancer diagnosed, of which 28 were positive tumor markers, accounting for about 59.6%, low-risk group and the detection of tumor markers were negative in a total of 52 cases, after follow-up pathology Two cases diagnosed as lung cancer, accounting for 3.8%, were statistically significant compared with those in middle and high risk group (P <0.05). Conclusion CT combined with serum tumor markers can improve the accuracy of early diagnosis of lung cancer, which has important clinical significance.