Quercetin alleviates high glucose-induced Schwann cell damage by autophagy

• 作 者: Ling Qu Xiaochun Liang Bei GU
• 机 构: DepartmentofTraditionalChineseMedicine,CellCenter
• 出 处: 中国神经再生研究：英文版
• 发表日期: 2014年12期
• 关键词: 细胞损伤 槲皮素 自噬 诱导 高糖 神经保护作用 雪旺氏细胞 周围神经 nerve regeneration quercetin diabetic periph
• 基金项目: supported by the National Natural Science Foundation of China,No.30572438,the Beijing Science Nuture Foundation,No.7132189,a grant from Science Foundation of Peking Union Medical College Hospital,No.2

Quercetin can reverse high glucose-induced inhibition of neural cell proliferation, and therefore may have a neuroprotective effect in diabetic peripheral neuropathy. It is difficult to obtain primary Schwann cells and RSC96 cells could replace primary Sc