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卡马西平(Carbamazepine,CBZ)又称酷胺咪嗪、痛惊宁,是临床上常用的抗癫痫药,还用于治疗三叉神经痛、舌咽神经痛及神经源性尿崩症,各类精神病如躁郁症、癫痫性精神病、精神分裂症,快速心律失常偏侧面肌痉挛、耳鸣等,并且是治疗精神运动性癫痫和三叉神经痛的首选药物,临床上应用很广泛,但在广泛应用的同时,亦不断发现了其诸多的药品不良反应,且有些不良反应是致命性的,在此特将近年来国内外报道的卡马西平药品不良反应做一综述,以提醒临床用药时注意.早期的研究报道认为,卡马西平副作用较少,主要为困倦、晕厥、胃肠反应,轻度皮肤损伤,轻度可逆性白细胞减少和运动障碍等.国外有人报道,服用卡马西平的人,60%左右出现某种副作用,一般不重,不需中断治疗,但近年来,国内外陆续报道了下列药品不良反应.
Carbamate (Carbamazepine, CBZ), also known as reminder of narcotine, is commonly used in clinical antiepileptic drugs, but also for the treatment of trigeminal neuralgia, glossopharyngeal neuralgia and neurogenic diabetes insipidus, various types Psychotic disorders such as bipolar disorder, epilepsy, schizophrenia, tachypnea, hemifacial spasm, tinnitus, and is the treatment of psychomotor epilepsy and trigeminal neuralgia drug of choice, the clinical application is very broad, but in a wide range of applications At the same time, it also found many of its adverse drug reactions, and some adverse reactions are fatal, especially in recent years, domestic and international reports of carbamazepine adverse drug reactions to do a review, to remind the attention of clinical medication. Of the study reported that fewer side effects of carbamazepine, mainly drowsiness, fainting, gastrointestinal reactions, mild skin damage, mild reversible leukopenia and dyskinesia etc. It was reported abroad, taking carbamazepine, 60 % Some side effects appear, generally not heavy, without interruption treatment, but in recent years, at home and abroad have reported the following adverse drug reactions.